Dysregulated expression of tumor necrosis factor in chronic fatigue syndrome: interrelations with cellular sources and patterns of soluble immune mediator expression.

@article{Patarca1994DysregulatedEO,
  title={Dysregulated expression of tumor necrosis factor in chronic fatigue syndrome: interrelations with cellular sources and patterns of soluble immune mediator expression.},
  author={Roberto Patarca and Nancy G. Klimas and S Lugtendorf and Michael Antoni and Mary Ann Fletcher},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={1994},
  volume={18 Suppl 1},
  pages={S147-53}
}
Among a group of 70 individuals who met the criteria established by the Centers for Disease Control and Prevention (Atlanta) for chronic fatigue syndrome (CFS), 12%-28% had serum levels exceeding 95% of control values for tumor necrosis factor (TNF) alpha, TNF-beta, interleukin (IL) 1 alpha, IL-2, soluble IL-2 receptor (sIL-2R), or neopterin; overall, 60% of patients had elevated levels of one or more of the nine soluble immune mediators tested. Nevertheless, only the distributions for… CONTINUE READING
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