Dysregulated expression of Fau and MELK is associated with poor prognosis in breast cancer

@article{Pickard2008DysregulatedEO,
  title={Dysregulated expression of Fau and MELK is associated with poor prognosis in breast cancer},
  author={Mark R. Pickard and Andrew R. Green and Ian O. Ellis and Carlos Caldas and Vanessa L Hedge and Mirna Mourtada-Maarabouni and Gwyn T. Williams},
  journal={Breast Cancer Research : BCR},
  year={2008},
  volume={11},
  pages={R60 - R60}
}
Programmed cell death through apoptosis plays an essential role in the hormone-regulated physiological turnover of mammary tissue. Failure of this active gene-dependent process is central both to the development of breast cancer and to the appearance of the therapy-resistant cancer cells that produce clinical relapse. Functional expression cloning in two independent laboratories has identified Finkel–Biskis–Reilly murine sarcoma virus-associated ubiquitously expressed gene (Fau) as a novel… CONTINUE READING

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Polygenes, risk prediction, and targeted prevention of breast cancer.

The New England journal of medicine • 2008
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