Dysregulated Wnt signalling and recurrent mutations of the tumour suppressor RNF43 in early gastric carcinogenesis.

Abstract

Several recurrent mutations and epigenetic changes have been identified in advanced gastric cancer, but the genetic alterations associated with early gastric carcinogenesis and malignant transformation remain unclear. We investigated the genomic and transcriptomic landscape of adenomas with low-grade dysplasia (LGD) and high-grade dysplasia (HGD), and… (More)
DOI: 10.1002/path.4777

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Cite this paper

@article{Min2016DysregulatedWS, title={Dysregulated Wnt signalling and recurrent mutations of the tumour suppressor RNF43 in early gastric carcinogenesis.}, author={Byung-Hoon Min and JinHa Hwang and Nayoung Kd Kim and Gibeom Park and So Young Kang and Sangjeong Ahn and Soomin Ahn and Sang Yun Ha and Yun Kyung Lee and Ryoji Kushima and Michael J Van Vrancken and Min Jung Kim and Changho Park and Ha Young Park and Jeesoo Chae and Se Song Jang and Sung Jin Kim and Young Ho Kim and Jong-Il Kim and Kyoung-Mee Kim}, journal={The Journal of pathology}, year={2016}, volume={240 3}, pages={304-314} }