Dysregulated MicroRNA Involvement in Multiple Sclerosis by Induction of T Helper 17 Cell Differentiation

@inproceedings{Chen2018DysregulatedMI,
  title={Dysregulated MicroRNA Involvement in Multiple Sclerosis by Induction of T Helper 17 Cell Differentiation},
  author={Chen Chen and Yifan Zhou and Jingqi Wang and Yaping Yan and Lisheng Peng and Wei Qiu},
  booktitle={Front. Immunol.},
  year={2018}
}
Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the central nervous system. Growing evidence has proven that T helper 17 (Th17) cells are one of the regulators of neuroinflammation mechanisms in MS disease. Researchers have demonstrated that some microRNAs (miRNAs) are associated with disease activity and duration, even with different MS patterns. miRNAs regulate CD4+ T cells to differentiate toward various T cell subtypes including Th17 cells. In this review, we discuss… CONTINUE READING

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