Dysmenorrhea and its severity are associated with increased uterine contractility and overexpression of oxytocin receptor (OTR) in women with symptomatic adenomyosis.

@article{Guo2013DysmenorrheaAI,
  title={Dysmenorrhea and its severity are associated with increased uterine contractility and overexpression of oxytocin receptor (OTR) in women with symptomatic adenomyosis.},
  author={Sun-wei Guo and Xiaoyan Mao and Qingliang Ma and Xishi Liu},
  journal={Fertility and sterility},
  year={2013},
  volume={99 1},
  pages={231-40}
}
OBJECTIVE To evaluate uterine contractility, oxytocin receptor (OTR) expression in myometrial smooth muscle cells (MSMCs) derived from uterine tissues from women with and without adenomyosis correlate OTR expression with uterine contractility and dysmenorrhea severity, and see whether trichostatin A (TSA) and andrographolide inhibit OTR expression. DESIGN Laboratory study using human tissues. SETTING Academic hospital. PATIENT(S) Twenty patients (cases) with histologically confirmed… CONTINUE READING

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Team

  • R Development Cor
  • R: a language and environment for statistical…
  • 2011

Antinociceptive and antiedematogenic activities of andrographolide isolated from Andrographis paniculata in animal models

  • MR Sulaiman, ZA Zakaria, A Abdul Rahman, AS Mohamad, MN Desa, J Stanslas
  • Biol Res Nurs
  • 2010
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