Dyslipidaemia in nephrotic syndrome: mechanisms and treatment

  title={Dyslipidaemia in nephrotic syndrome: mechanisms and treatment},
  author={Shipra Agrawal and Joshua Jacob Zaritsky and Alessia Fornoni and William E. Smoyer},
  journal={Nature Reviews Nephrology},
Nephrotic syndrome is a highly prevalent disease that is associated with high morbidity despite notable advances in its treatment. Many of the complications of nephrotic syndrome, including the increased risk of atherosclerosis and thromboembolism, can be linked to dysregulated lipid metabolism and dyslipidaemia. These abnormalities include elevated plasma levels of cholesterol, triglycerides and the apolipoprotein B-containing lipoproteins VLDL and IDL; decreased lipoprotein lipase activity in… CONTINUE READING
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