Dyslexia-specific brain activation profile becomes normal following successful remedial training

  title={Dyslexia-specific brain activation profile becomes normal following successful remedial training},
  author={Panagiotis G. Simos and Judy Fletcher and E Bergman and Joshua I. Breier and Barbara R. Foorman and E. M. Castillo and Robert N. Davis and Michele E. Fitzgerald and Andrew C. Papanicolaou},
Objectives To examine changes in the spatiotemporal brain activation profiles associated with successful completion of an intensive intervention program in individual dyslexic children. Methods The authors obtained magnetic source imaging scans during a pseudoword reading task from eight children (7 to 17 years old) before and after 80 hours of intensive remedial instruction. All children were initially diagnosed with dyslexia, marked by severe difficulties in word recognition and phonologic… 

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  • S. ShaywitzB. Shaywitz J. Gore
  • Psychology, Biology
    Proceedings of the National Academy of Sciences of the United States of America
  • 1998
Using functional magnetic resonance imaging to compare brain activation patterns in dyslexic and nonimpaired subjects as they performed tasks that made progressively greater demands on phonologic analysis supports a conclusion that the impairment in Dyslexia is phonologic in nature.

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Functional magnetic resonance imaging results identify left prefrontal regions as normally being sensitive to rapid relative to slow acoustic stimulation, insensitive to the difference between such stimuli in dyslexic readers, and plastic enough in adulthood to develop such differential sensitivity after intensive training.

Disrupted neural responses to phonological and orthographic processing in dyslexic children: an fMRI study

FMRI was performed on dyslexic and normal-reading children during phonological and orthographic tasks of rhyming and matching visually presented letter pairs to indicate dyslexia may be characterized in childhood by disruptions in the neural bases of both phonologicaland orthographic processes important for reading.

Normal activation of frontotemporal language cortex in dyslexia, as measured with oxygen 15 positron emission tomography.

These results, together with the previously reported failure of dyslexics to activate left temporoparietal cortex during phonologic processing, argue for dysfunction of left cortical language areas restricted to posterior language regions in dyslexia.

Failure to activate the left temporoparietal cortex in dyslexia. An oxygen 15 positron emission tomographic study.

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A positron emission tomographic study of impaired word recognition and phonological processing in dyslexic men.

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