Dysfunction of a distributed neural circuitry in schizophrenia patients during a working-memory performance.

@article{Mendrek2005DysfunctionOA,
  title={Dysfunction of a distributed neural circuitry in schizophrenia patients during a working-memory performance.},
  author={Adrianna Mendrek and Kent A. Kiehl and Andra Smith and David Irwin and Bruce B. Forster and Peter F. Liddle},
  journal={Psychological medicine},
  year={2005},
  volume={35 2},
  pages={187-96}
}
BACKGROUND In a recent longitudinal study of first-episode schizophrenia patients, we found that while dysfunction of the right dorsolateral prefrontal cortex (DLPFC), right thalamus, left cerebellum and cingulate gyrus normalized with antipsychotic treatment and significant reduction in symptomatology, the left DLPFC, left thalamus, and right cerebellum remained disturbed. In the present study we investigated whether these abnormalities are also present in clinically stable, relatively well… CONTINUE READING
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PET evidence for a dissociation between the storage and rehearsal components of verbal working memory

  • E. Awh, J. Jonides, E. E. Smith, E. H. Schumacher, R. A. Koeppe
  • Psychological Sciences
  • 1996
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