Dysfunction in the neural circuitry of emotion regulation--a possible prelude to violence.

@article{Davidson2000DysfunctionIT,
  title={Dysfunction in the neural circuitry of emotion regulation--a possible prelude to violence.},
  author={Richard J. Davidson and Katherine M. Putnam and Christine L. Larson},
  journal={Science},
  year={2000},
  volume={289 5479},
  pages={
          591-4
        }
}
Emotion is normally regulated in the human brain by a complex circuit consisting of the orbital frontal cortex, amygdala, anterior cingulate cortex, and several other interconnected regions. There are both genetic and environmental contributions to the structure and function of this circuitry. We posit that impulsive aggression and violence arise as a consequence of faulty emotion regulation. Indeed, the prefrontal cortex receives a major serotonergic projection, which is dysfunctional in… 
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