Dyospiros kaki phenolics inhibit colitis and colon cancer cell proliferation, but not gelatinase activities.

@article{Direito2017DyospirosKP,
  title={Dyospiros kaki phenolics inhibit colitis and colon cancer cell proliferation, but not gelatinase activities.},
  author={Rosa Direito and Ana Isabel Gusm{\~a}o Lima and Jo{\~a}o Rocha and Ricardo Boavida Ferreira and Joana Decq Mota and Patr{\'i}cia Rebelo and Adelaide Fernandes and Rui Pinto and Paula de Assis Pereira Alves and Ros{\'a}rio Bronze and Bruno Sepodes and M E Figueira},
  journal={The Journal of nutritional biochemistry},
  year={2017},
  volume={46},
  pages={100-108}
}
Polyphenols from persimmon (Diospyros kaki) have demonstrated radical-scavenging and antiinflammatory activities; however, little is known about the effects of persimmon phenolics on inflammatory bowel diseases (IBD) and colorectal cancer (CRC). Therefore, we aimed in this work to characterize the antiinflammatory and antiproliferative effects of a persimmon phenolic extract (80% acetone in water), using an in vivo model of experimental colitis and a model of cancer cell invasion. Our results… CONTINUE READING