Dynamin-mediated Internalization of Caveolae

  title={Dynamin-mediated Internalization of Caveolae },
  author={John R. Henley and Eugene W Krueger and Barbara J. Oswald and Mark A. McNiven},
  journal={The Journal of Cell Biology},
  pages={85 - 99}
The dynamins comprise an expanding family of ubiquitously expressed 100-kD GTPases that have been implicated in severing clathrin-coated pits during receptor-mediated endocytosis. Currently, it is unclear whether the different dynamin isoforms perform redundant functions or participate in distinct endocytic processes. To define the function of dynamin II in mammalian epithelial cells, we have generated and characterized peptide-specific antibodies to domains that either are unique to this… CONTINUE READING
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