Dynamin 3 Is a Component of the Postsynapse, Where it Interacts with mGluR5 and Homer

  title={Dynamin 3 Is a Component of the Postsynapse, Where it Interacts with mGluR5 and Homer},
  author={Noah W. Gray and Lawrence Fourgeaud and Bing Huang and Jing Chen and Hong L Cao and Barbara J. Oswald and Agn{\`e}s H{\'e}mar and Mark A. McNiven},
  journal={Current Biology},
The dynamins comprise a large family of mechanoenzymes known to participate in membrane modeling events. All three conventional dynamin genes (Dyn1, Dyn2, Dyn3) are expressed in mammalian brain and produce more than 27 different dynamin proteins as a result of alternative splicing. Past studies have suggested that Dyn1 participates in specialized neuronal functions such as rapid synaptic vesicle recycling, while Dyn2 may mediate the conventional clathrin-mediated uptake of surface receptors… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 58 extracted citations

Evolutionary Insights into Premetazoan Functions of the Neuronal Protein Homer

Molecular biology and evolution • 2014
View 4 Excerpts
Highly Influenced

A role for dynamin in triggering ethanol tolerance.

Alcoholism, clinical and experimental research • 2012
View 5 Excerpts
Highly Influenced


Publications referenced by this paper.
Showing 1-10 of 22 references

Pinching in new places: multiple functions for the dynamin family

M. A. McNiven, H. Cao, K. R. Pitts, Y. Yoon
Trends Note Added in Proof • 2000
View 14 Excerpts
Highly Influenced

The metabotropic glutamate receptorbution of dynamin isoforms in mammalian cells

A. Hemar
Mol . Biol . Cell • 2003

Dynamin 2 and cortactin regulate actin assemblythe need for multiple dynamins to perform specialized and filament organization

T. Nakata, R. Takemura, N. Hirokawa
Curr . Biol . • 2002

Dynamin at actin tails.

Proceedings of the National Academy of Sciences of the United States of America • 2002

unpublished data ) may imply that Dyn 3 is acting through The large GTPase dynamin regulates actin comet formation andan actindependent network in order to induce these movement in living cells

M. A. McNiven
Proc . Natl . Acad . Sci . USA • 2002

Dynamin family of mechaThe data referred to as L.F

D. Danino, J. E. Hinshaw

Dynamin isoformspecific interaction with the shank / Accepted : January 20 , 2003 ProSAP scaffolding proteins of the postsynaptic density and Published : March 18 , 2003 actin cytoskeleton

G. C. Ochoa, V. I. Slepnev, +6 authors R. Baron
J . Biol . Chem . • 2000

References A functional link between dynamin and the actin cytoskeleton at podosomes

M. A. McNiven, H. Cao, K. R. Pitts, Y. Yoon
J . Cell Biol . • 2000

Differential distriJ.C., and Hemar, A

H. Cao, F. Garcia, M. A. McNiven

Dynamin family of mechaThe data referred to as L . F . et al . , submitted are now in press : noenzymes

L. Fourgeaud, A. S. Bessis, +4 authors M. A. McNiven
Curr . Opin . Cell Biol . • 1998

Similar Papers

Loading similar papers…