Dynamin 2 interacts with connexin 26 to regulate its degradation and function in gap junction formation.

Abstract

Connexin 26 (Cx26), a protein involved in gap junctional intercellular communication, has an essential function during organ and tissue development. Its deregulation, in part due to inherent mutations, is associated with pathological conditions including congenital deafness. Regulation of Cx26 protein level is critical for its function but the molecular… (More)
DOI: 10.1016/j.biocel.2014.09.021

Topics

5 Figures and Tables

Slides referencing similar topics