• DOI:10.1021/cr020689l
Corpus ID: 10050118

Dynamics of water in biological recognition.

@article{Pal2004DynamicsOW,
  title={Dynamics of water in biological recognition.},
  author={S. Pal and A. Zewail},
  journal={Chemical reviews},
  year={2004},
  volume={104 4},
  pages={
          2099-123
        }
}

S. Pal, A. Zewail

Published 2004

Chemistry, Medicine

Chemical reviews

Almost all biological macromoleculess proteins (enzymes) and DNAs are inactive in the absence of water. Hydration of a protein/enzyme is particularly important for the stability of the structure and for the function, especially the recognition at a specific site. This role of hydration in enzyme catalysis is well known and has recently been reviewed in a number of publications. In one of these studies it was shown that the dehydration of a protein, which makes it more rigid and… CONTINUE READING

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