Dynamics of water in biological recognition.
@article{Pal2004DynamicsOW, title={Dynamics of water in biological recognition.}, author={Samir Kumar Pal and Ahmed H. Zewail}, journal={Chemical reviews}, year={2004}, volume={104 4}, pages={ 2099-123 } }
Almost all biological macromoleculess proteins
(enzymes) and DNAs are inactive in the absence of
water. Hydration of a protein/enzyme is particularly
important for the stability of the structure and for
the function, especially the recognition at a specific
site. This role of hydration in enzyme catalysis is well
known and has recently been reviewed in a number
of publications. In one of these studies it was
shown that the dehydration of a protein, which
makes it more rigid and…
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