Dynamics of therapeutic ultrasound contrast agents.

  title={Dynamics of therapeutic ultrasound contrast agents.},
  author={John S. Allen and Donovan J May and Katherine W. Ferrara},
  journal={Ultrasound in medicine & biology},
  volume={28 6},
Novel therapeutic contrast agents offer great potential for localized drug delivery. Localized delivery should significantly improve the efficacy of drug delivery and reduce any toxic exposure to the healthy tissue. This work describes a preliminary theoretical description of agents, such as those developed by the ImaRx Corporation, enclosed by a relatively thick fluid shell. A theoretical extension is made to a generalized Rayleigh-Plesset formulation that allows it to be solved for an… CONTINUE READING

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