Dynamics of the sub-nuclear distribution of Modulo and the regulation of position-effect variegation by nucleolus in Drosophila.

@article{Perrin1998DynamicsOT,
  title={Dynamics of the sub-nuclear distribution of Modulo and the regulation of position-effect variegation by nucleolus in Drosophila.},
  author={Laurent Perrin and Olga V. Demakova and Laura Fanti and Sacha Kallenbach and S Saingery and Natalia I Mal'ceva and Sergio Pimpinelli and Igor Zhimulev and Jacques Pradel},
  journal={Journal of cell science},
  year={1998},
  volume={111 ( Pt 18)},
  pages={2753-61}
}
modulo belongs to the class of Drosophila genes named 'suppressor of position-effect variegation', suggesting the involvement of the encoded protein in chromatin compaction/relaxation processes. Using complementary procedures of cell fractionation, immunolocalisation on mitotic and polytene chromosomes and cross-linking/immunoprecipitation of genomic DNA targets, we have analysed the sub-nuclear distribution of Modulo. While actually associated to condensed chromatin and heterochromatin sites… CONTINUE READING
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The Genome of Drosophila

  • D. T. Lindsley, G. G. Zimm
  • 1992
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