Dynamics of the cell and its extracellular matrix - a simple mathematical approach

  title={Dynamics of the cell and its extracellular matrix - a simple mathematical approach},
  author={A. K. Saha and J. Mazumdar},
  journal={IEEE Transactions on NanoBioscience},
The extracellular matrix (ECM) is produced by the cells and secreted into the surrounding medium, and consists of a complex mixture of structural and functional proteins. It has been recently observed that the ECM can influence the behavior of cell growth in vitro quite remarkably. A simple mathematical model has been constructed based on negative feedback control mechanisms to represent the dynamics of ECM deposition and cellular differentiation. The model analysis shows a strong relationship… CONTINUE READING


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