Dynamics of the Complement, Cytokine, and Chemokine Systems in the Regulation of Synaptic Function and Dysfunction Relevant to Alzheimer's Disease.

@article{Jiang2017DynamicsOT,
  title={Dynamics of the Complement, Cytokine, and Chemokine Systems in the Regulation of Synaptic Function and Dysfunction Relevant to Alzheimer's Disease.},
  author={Shanya Jiang and Kiran Bhaskar},
  journal={Journal of Alzheimer's disease : JAD},
  year={2017},
  volume={57 4},
  pages={
          1123-1135
        }
}
Alzheimer's disease (AD) is the most common form of dementia affecting nearly 45 million people worldwide. However, the etiology of AD is still unclear. Accumulations of amyloid-β plaques and tau tangles, neuroinflammation, and synaptic and neuronal loss are the major neuropathological hallmarks of AD, with synaptic loss being the strongest correlating… CONTINUE READING