Dynamics of telomerase activity in response to acute psychological stress.

@article{Epel2010DynamicsOT,
  title={Dynamics of telomerase activity in response to acute psychological stress.},
  author={Elissa S Epel and Jue Lin and Firdaus S. Dhabhar and Owen M. Wolkowitz and Eli Puterman and Lori Karan and Elizabeth H Blackburn},
  journal={Brain, behavior, and immunity},
  year={2010},
  volume={24 4},
  pages={531-9}
}
Telomerase activity plays an essential role in cell survival, by lengthening telomeres and promoting cell growth and longevity. It is now possible to quantify the low levels of telomerase activity in human leukocytes. Low basal telomerase activity has been related to chronic stress in people and to chronic glucocorticoid exposure in vitro. Here we test whether leukocyte telomerase activity changes under acute psychological stress. We exposed 44 elderly women, including 22 high stress dementia… CONTINUE READING