Dynamics of serum procalcitonin in patients after major neurosurgery.

  title={Dynamics of serum procalcitonin in patients after major neurosurgery.},
  author={Gerd Laifer and Maria Wasner and Pedram Sendi and Peter Graber and Otmar Gratzl and Peter Huber and Ursula Fl{\'u}ckiger and Werner Zimmerli},
  journal={Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases},
  volume={11 8},
Classical markers of infection cannot differentiate reliably between inflammation and infection after neurosurgery. This study investigated the dynamics of serum procalcitonin (PCT) in patients following major neurosurgery. PCT concentrations remained < 0.2 ng/mL during the post-operative course. In contrast, leukocyte and neutrophil counts, as well as C-reactive protein (CRP) levels, increased significantly post-operatively (leukocytes, range 7.1-23.7 x 10(9)/L, p < 0.001; neutrophils, range… CONTINUE READING

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