Dynamics of magnetic lipoplexes studied by single particle tracking in living cells.

@article{Sauer2009DynamicsOM,
  title={Dynamics of magnetic lipoplexes studied by single particle tracking in living cells.},
  author={Alexandra M Sauer and Karla de Bruin and Nadia Ruthardt and Olga Mykhaylyk and Christian Plank and C. Br{\"a}uchle},
  journal={Journal of controlled release : official journal of the Controlled Release Society},
  year={2009},
  volume={137 2},
  pages={136-45}
}
Magnetofection, gene delivery under the influence of a magnetic field, is a technique to increase transfection efficiency by enforcing gene vector contact with a target cell. Mechanisms of magnetic lipoplex internalization and intracellular details of magnetofection are still unknown. In this study, cellular dynamics of magnetic lipoplexes were examined in real time by means of highly sensitive dual-color fluorescence microscopy. Single particle tracking of magnetic lipoplexes provided… CONTINUE READING

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