Dynamics of immunoglobulins at the feto-maternal interface.

  title={Dynamics of immunoglobulins at the feto-maternal interface.},
  author={Fumitaka Saji and Yoshihiro Samejima and Shoji Kamiura and Masayasu Koyama},
  journal={Reviews of reproduction},
  volume={4 2},
Transplacental transport of maternal immunoglobulin G (IgG) to the developing fetus is extremely important in the protection of the newborn from infection. Although the exact mechanisms of the selective and active transfer of IgG across the placental barrier are not fully understood, receptors for the Fc part of IgG (FcgammaRs) in the placenta are believed to play a key role. Several known Fc receptors, FcgammaRI, FcgammaRII, FcgammaRIII and FcRn (neonatal FcR), demonstrate heterogeneous… 

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