Dynamics of immediate early gene and neuropeptide gene response to prolonged immobilization stress: evidence against a critical role of the termination of exposure to the stressor.

@article{Trneckov2007DynamicsOI,
  title={Dynamics of immediate early gene and neuropeptide gene response to prolonged immobilization stress: evidence against a critical role of the termination of exposure to the stressor.},
  author={Lenka Trneckov{\'a} and David Rotllant and Vera Klenerova and Sixtus Hynie and Antonio Armario},
  journal={Journal of neurochemistry},
  year={2007},
  volume={100 4},
  pages={905-14}
}
Stress-induced expression of immediate early genes (IEGs) appears to be transient even if the exposure to the stressor persists. However, there are some exceptions which suggest that particular characteristics of stressors can affect the dynamics of IEG expression. We studied in selected telencephalic, diencephalic and brainstem regions the mRNA levels of two clearly distinct IEGs (c-fos and arc) during prolonged exposure to a severe stressor such as immobilization (IMO) and after releasing the… CONTINUE READING

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Long-term effects of a single exposure to immobilization: a c-Fos mRNA study of the response to the homotypic stressor in the rat

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