Dynamics of formation of primary and secondary lipid peroxidation products upon copper-dependent oxidation of low-density lipoproteins isolated from blood serum of patients with ischemic heart disease

Abstract

The kinetics of copper-induced oxidation of lipids in serum low-density lipoproteins from healthy subjects and patients with ischemic heart disease and documented coronary atherosclerosis is studied. After a 4-h incubation with 40 μM CuSO4, the oxidizability of patients' lipoproteins is higher, judging from the contents of diene conjugates and oxidation… (More)
DOI: 10.1007/BF02446020

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