Dynamics of dendritic spines and their afferent terminals: spines are more motile than presynaptic boutons.

@article{Deng2005DynamicsOD,
  title={Dynamics of dendritic spines and their afferent terminals: spines are more motile than presynaptic boutons.},
  author={Jinbo Deng and A Dunaevsky},
  journal={Developmental biology},
  year={2005},
  volume={277 2},
  pages={366-77}
}
Previous work has established that dendritic spines, sites of excitatory input in CNS neurons, can be highly dynamic, in later development as well as in mature brain. Although spine motility has been proposed to facilitate the formation of new synaptic contacts, we have reported that spines continue to be dynamic even if they bear synaptic contacts. An outstanding question related to this finding is whether the presynaptic terminals that contact dendritic spines are as dynamic as their… CONTINUE READING