Dynamics of cell surface molecules during T cell recognition.

  title={Dynamics of cell surface molecules during T cell recognition.},
  author={Mark M. Davis and Michelle Krogsgaard and Johannes B. Huppa and Cenk Sumen and Marco A. Purbhoo and Darrell J Irvine and Lawren C. Wu and Lauren I R Ehrlich},
  journal={Annual review of biochemistry},
Recognition of foreign antigens by T lymphocytes is a very important component of vertebrate immunity-vital to the clearance of pathogenic organisms and particular viruses and necessary, indirectly, for the production of high affinity antibodies. T cell recognition is mediated by the systematic scanning of cell surfaces by T cells, which collectively express many antigen receptors. When the appropriate antigenic peptide bound to a molecule of the major histocompatibility complex is found-even… CONTINUE READING
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