Dynamics of cell interactions and communications during melanoma development.

@article{Li2002DynamicsOC,
  title={Dynamics of cell interactions and communications during melanoma development.},
  author={Geming Li and Kapaettu Satyamoorthy and Meenhard Herlyn},
  journal={Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists},
  year={2002},
  volume={13 1},
  pages={
          62-70
        }
}
Melanoma development not only involves genetic and epigenetic changes that take place within the cell, but also involves processes determined collectively by micro-environmental factors, including cell-cell interactions and communications. During the transition from normal cells to benign and malignant lesions, and subsequently to metastatic cancer, stepwise changes in intercellular communications provide tumor cells with the ability to overcome cell-cell adhesion and micro-environmental… CONTINUE READING
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