Dynamics of calcium fluxes in human platelets assessed in calcium-free medium.

@article{Juka2005DynamicsOC,
  title={Dynamics of calcium fluxes in human platelets assessed in calcium-free medium.},
  author={Alfonsas Ju{\vs}ka and Pedro Cosme Redondo and Juan Antonio Rosado and Gin{\'e}s M Salido},
  journal={Biochemical and biophysical research communications},
  year={2005},
  volume={334 3},
  pages={779-86}
}
Dynamics of changes in cytosolic calcium concentration resulting from facilitation of calcium leakage from the stores and (or) blocking the pathways of its reuptake back into the stores or extrusion out of the cell (or both) have been investigated experimentally. It has been found that: (a) no mechanisms other than the membrane leakage, PMCA or SERCA, are involved in the discharge of calcium stores and calcium extrusion or reuptake; (b) the discharge of calcium stores in the absence of both its… CONTINUE READING