Dynamics of an idealized model of microtubule growth and catastrophe.

@article{Antal2007DynamicsOA,
  title={Dynamics of an idealized model of microtubule growth and catastrophe.},
  author={Tibor Antal and Pavel L. Krapivsky and Sidney Redner and Mitchell Douglas Mailman and Bulbul Chakraborty},
  journal={Physical review. E, Statistical, nonlinear, and soft matter physics},
  year={2007},
  volume={76 4 Pt 1},
  pages={
          041907
        }
}
We investigate a simple dynamical model of a microtubule that evolves by attachment of guanosine triphosphate (GTP) tubulin to its end, irreversible conversion of GTP to guanosine diphosphate (GDP) tubulin by hydrolysis, and detachment of GDP at the end of a microtubule. As a function of rates of these processes, the microtubule can grow steadily or its length can fluctuate wildly. In the regime where detachment can be neglected, we find exact expressions for the tubule and GTP cap length… CONTINUE READING
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