Dynamics of Phosphoinositide-Dependent Signaling in Sympathetic Neurons.

@article{Kruse2016DynamicsOP,
  title={Dynamics of Phosphoinositide-Dependent Signaling in Sympathetic Neurons.},
  author={Martin Kruse and Oscar Vivas and Alexis E. Traynor-Kaplan and Bertil Hille},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2016},
  volume={36 4},
  pages={1386-400}
}
UNLABELLED In neurons, loss of plasma membrane phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2] leads to a decrease in exocytosis and changes in electrical excitability. Restoration of PI(4,5)P2 levels after phospholipase C activation is therefore essential for a return to basal neuronal activity. However, the dynamics of phosphoinositide metabolism have… CONTINUE READING