Dynamics of HIV tropism under suppressive antiretroviral therapy: implications for tropism testing in subjects with undetectable viraemia.

@article{Secln2010DynamicsOH,
  title={Dynamics of HIV tropism under suppressive antiretroviral therapy: implications for tropism testing in subjects with undetectable viraemia.},
  author={Eduardo Secl{\'e}n and Mar{\'i}a del Mar Gonz{\'a}lez and Carmen de Mendoza and Vicente Soriano and Eva Poveda},
  journal={The Journal of antimicrobial chemotherapy},
  year={2010},
  volume={65 7},
  pages={1493-6}
}
OBJECTIVES The use of maraviroc as part of a simplification of antiretroviral therapy (ART) is hampered by the difficulty of assessing viral tropism in patients with undetectable viraemia. In this context, information on tropism might be obtained from testing either older stored viraemic sera collected before initiation of ART or current proviral DNA in peripheral blood cells. METHODS HIV-1-infected individuals who had initiated ART and had undetectable viraemia for >2 years were identified… CONTINUE READING
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