Dynamics of Excitability over Extended Timescales in Cultured Cortical Neurons

@article{Gal2010DynamicsOE,
  title={Dynamics of Excitability over Extended Timescales in Cultured Cortical Neurons},
  author={Asaf Gal and D. Eytan and A. Wallach and Maya Sandler and J. Schiller and Shimon Marom},
  journal={The Journal of Neuroscience},
  year={2010},
  volume={30},
  pages={16332 - 16342}
}
Although neuronal excitability is well understood and accurately modeled over timescales of up to hundreds of milliseconds, it is currently unclear whether extrapolating from this limited duration to longer behaviorally relevant timescales is appropriate. Here we used an extracellular recording and stimulation paradigm that extends the duration of single-neuron electrophysiological experiments, exposing the dynamics of excitability in individual cultured cortical neurons over timescales… Expand
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