Dynamics and regulation of intracellular thyroid hormone concentrations in embryonic chicken liver, kidney, brain, and blood.

@article{Reyns2003DynamicsAR,
  title={Dynamics and regulation of intracellular thyroid hormone concentrations in embryonic chicken liver, kidney, brain, and blood.},
  author={Geert E Reyns and Katrien Venken and Gabriella Morreale de Escobar and Eduard R. K{\"u}hn and Veerle M. Darras},
  journal={General and comparative endocrinology},
  year={2003},
  volume={134 1},
  pages={80-7}
}
The intracellular thyroid hormone (TH) availability is influenced by different metabolic pathways. We investigated the relationship between tissue and plasma TH levels as well as the correlation with changes of deiodination and sulfation during chicken embryonic development. From day 14 until day 19, T3 remains unchanged in liver and kidney in spite of increasing plasma T4 and T3 levels and a slightly increased T4 availability in these tissues. During this period, the T3 breakdown capacity by… CONTINUE READING