Dynamics and participation of type II phospholipase A2 in rat zymosan-induced pleurisy.

@article{Hara1993DynamicsAP,
  title={Dynamics and participation of type II phospholipase A2 in rat zymosan-induced pleurisy.},
  author={Shuuji Hara and Yasuyuki Imai and Makoto Murakami and Hiroki Mori and Ken-ichi Takahashi and Ichiro Kudo and Hiroaki Naraba and Sachiko Oh-ishi and Keizo Inoue},
  journal={Journal of biochemistry},
  year={1993},
  volume={114 4},
  pages={509-12}
}
Intrapleural injection of zymosan into rats induces acute inflammation characterized by plasma leakage and cellular influx. The level of type II phospholipase A2 (PLA2) increased in the pleural fluid as well as in exudating leukocytes after the injection of zymosan. Rather low PLA2 activity was found in cell lysates, though treatment of such lysates at low… CONTINUE READING