Dynamics and modulation of human immunodeficiency virus type 1 transcripts in vitro and in vivo.

@article{Bagnarelli1996DynamicsAM,
  title={Dynamics and modulation of human immunodeficiency virus type 1 transcripts in vitro and in vivo.},
  author={Patrizia Bagnarelli and A. Valenza and Stefano Menzo and Riccardo Sampaolesi and Pietro Emanuele Varaldo and Luca Butini and Maria Montroni and Carlo Federico Perno and Stefano Aquaro and Dominique Mathez and Jacques L. Leibowitch and C Balotta and Massimo Clementi},
  journal={Journal of virology},
  year={1996},
  volume={70 11},
  pages={7603-13}
}
The dynamics of human immunodeficiency virus type 1 (HIV-1) transcription was analyzed in vitro and in vivo by using a specific molecular approach which allows accurate quantitation of the different classes of viral mRNAs. Unspliced (US) and multiply spliced (MS) HIV-1 transcripts were assayed by competitive reverse transcription (cRT)-PCR, using a single competitor RNA bearing in tandem internally deleted sequences of both template species. Acute HIV-1 infection of primary peripheral blood… CONTINUE READING
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