Corpus ID: 235422002

Dynamics and Sensitivity of Signaling Pathways

  title={Dynamics and Sensitivity of Signaling Pathways},
  author={Michael A. Kochen and S. Andrews and H. Wiley and Song Feng and H. Sauro},
Purpose of Review: Signaling pathways serve to communicate information about extracellular conditions into the cell, to both the nucleus and cytoplasmic processes to control cell responses. Genetic mutations in signaling network components are frequently associated with cancer and can result in cells acquiring an ability to divide and grow uncontrollably. Because signaling pathways play such a significant role in cancer initiation and advancement, their constituent proteins are attractive… Expand

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  • Biology, Medicine
  • Journal of The Royal Society Interface
  • 2017
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