Dynamics and Memory of Heterochromatin in Living Cells

@article{Hathaway2012DynamicsAM,
  title={Dynamics and Memory of Heterochromatin in Living Cells},
  author={Nathaniel A. Hathaway and Oliver Bell and Courtney Hodges and Erik Learned Miller and Dana S. Neel and Gerald R Crabtree},
  journal={Cell},
  year={2012},
  volume={149},
  pages={1447-1460}
}
Posttranslational histone modifications are important for gene regulation, yet the mode of propagation and the contribution to heritable gene expression states remains controversial. To address these questions, we developed a chromatin in vivo assay (CiA) system employing chemically induced proximity to initiate and terminate chromatin modifications in… CONTINUE READING