Dynamics and Control of the Central Carbon Metabolism in Hepatoma Cells

  title={Dynamics and Control of the Central Carbon Metabolism in Hepatoma Cells},
  author={Klaus Maier and Ute Hofmann and Matthias Reuss and Klaus Mauch},
  booktitle={BMC Systems Biology},
The liver plays a major role in metabolism and performs a number of vital functions in the body. Therefore, the determination of hepatic metabolite dynamics and the analysis of the control of the respective biochemical pathways are of great pharmacological and medical importance. Extra- and intracellular time-series data from stimulus-response experiments are gaining in importance in the identification of in vivo metabolite dynamics, while dynamic network models are excellent tools for… CONTINUE READING
17 Citations
93 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 17 extracted citations


Publications referenced by this paper.
Showing 1-10 of 93 references

Biochemistry, International Version Fifth edition

  • J Berg, J Tymoczko, L Stryer
  • New York: W.H. Freeman
  • 2002
Highly Influential
10 Excerpts

Regulatory responses and control analysis: assessment of the relative importance of internal effectors

  • HM Sauro
  • In Control of Metabolic Processes Edited by…
  • 1990
Highly Influential
4 Excerpts

Similar Papers

Loading similar papers…