Dynamic upregulation of CD24 in pre-adipocytes promotes adipogenesis.

  title={Dynamic upregulation of CD24 in pre-adipocytes promotes adipogenesis.},
  author={Nicole C P Smith and Nicholas A. Fairbridge and Nikitha K. Pallegar and Sherri L Christian},
  volume={4 2},
The development of mature adipocytes from pre-adipocytes is a highly regulated process. CD24 is a glycophosphatidylinositol-linked cell surface receptor that has been identified as a critical cell surface marker for identifying pre-adipocytes that are able to reconstitute white adipose tissue (WAT) in vivo. Here, we examined the role and regulation of CD24 during adipogenesis in vitro. We found that CD24 mRNA and protein expression is upregulated early during adipogenesis in the 3T3-L1 pre… CONTINUE READING


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