Dynamic restricted expression of the chaperone Hsc70 in early chick development

  title={Dynamic restricted expression of the chaperone Hsc70 in early chick development},
  author={Elena Vega-N{\'u}{\~n}ez and Angel Pe{\~n}A-Melian and E. La Rosa and Flora de Pablo},
  journal={Mechanisms of Development},
The non-inducible chaperone heat shock cognate 70 kDa (Hsc70) is regulated during development. We now characterize its dynamic expression pattern from gastrulation to early organogenesis. Throughout this developmental period, hsc70 transcripts were largely restricted to neuroectoderm- and mesoderm-derived structures. In stage 10 embryos, Hsc70 protein was expressed in the neural tube with increasing rostrocaudal and decreasing dorsoventral gradients, and in some somite cells. This highly… CONTINUE READING


Publications referenced by this paper.
Showing 1-10 of 15 references

Heat shock proteins in retinal neuro

  • F. Pablo, E. J. De la Rosa
  • 1998

Modulation of the chaperone heat shock cognate 70 by embryonic (pro)insulin correlates with prevention of apoptosis

  • E. ́ñez, A. V. Morales, J. Serna, E. Rubio, F. De Pablo
  • Proc. Natl. Acad. Sci. USA
  • 1998

The function of heat - shock proteins in stress tolerance : degradation and reactivation of damaged proteins

  • J. Rassow, O. Von Ahsen, U. Bömer, N. Pfanner
  • Annu . Rev . Genet .
  • 1997
1 Excerpt

Similar Papers

Loading similar papers…