Dynamic regulation of the structure and functions of integrin adhesions.

  title={Dynamic regulation of the structure and functions of integrin adhesions.},
  author={Haguy Wolfenson and Irena Lavelin and Benjamin Geiger},
  journal={Developmental cell},
  volume={24 5},
Integrin-mediated cell adhesions to the extracellular matrix (ECM) contribute to tissue morphogenesis and coherence and provide cells with vital environmental cues. These apparently static structures display remarkable plasticity and dynamic properties: they exist in multiple, interconvertible forms that are constantly remodeled in response to changes in ECM properties, cytoskeletal organization, cell migration, and signaling processes. Thus, integrin-mediated environmental sensing enables… CONTINUE READING
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