Dynamic nuclear polarization NMR spectroscopy: revealing multiple conformations in lipid-anchored peptide vaccines.

@article{Koers2013DynamicNP,
  title={Dynamic nuclear polarization NMR spectroscopy: revealing multiple conformations in lipid-anchored peptide vaccines.},
  author={Eline J Koers and Mar{\'i}a Pilar L{\'o}pez-Deber and Markus Weingarth and Deepak Nand and David T. Hickman and Dorin Mlaki Ndao and Pedro Reis and Anne Granet and A. Pfeifer and Andreas Muhs and Marc Baldus},
  journal={Angewandte Chemie},
  year={2013},
  volume={52 41},
  pages={10905-8}
}
Many pharmacological properties of conventional drugs can be improved using drug delivery systems, which are composed primarily of polymers or lipids. Liposomes have become versatile delivery systems for induction of antibody and Tlymphocyte responses to associated subunit antigens. The resulting immune response depends on the structural and physicochemical properties of liposomal vaccines. Biophysical methods, including circular dichroism (CD) or attenuated total reflectance IR spectroscopy… CONTINUE READING

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