Dynamic noise, chaos and parameter estimation in population biology.

  title={Dynamic noise, chaos and parameter estimation in population biology.},
  author={Nico Stollenwerk and Maı́ra Aguiar and S{\'e}bastien Ballesteros and Jos{\'e} Boto and Bob Kooi and Lu{\'i}s Mateus},
  journal={Interface focus},
  volume={2 2},
We revisit the parameter estimation framework for population biological dynamical systems, and apply it to calibrate various models in epidemiology with empirical time series, namely influenza and dengue fever. When it comes to more complex models such as multi-strain dynamics to describe the virus-host interaction in dengue fever, even the most recently developed parameter estimation techniques, such as maximum likelihood iterated filtering, reach their computational limits. However, the first… CONTINUE READING