Dynamic morphological responses of mouse astrocytes in primary cultures following medium changes.

Within 5 minutes of changing the medium of 3-4 week old mouse astrocyte cultures, dramatic morphological alterations were seen in the cultures at the phase microscope level. These alterations included the appearance of membrane ruffles, followed by the formation of phase light vacuolar regions. Ultrastructurally, these ruffles could be seen as phagocytic… CONTINUE READING