Dynamic monitoring of glucagon secretion from living cells on a microfluidic chip.

Abstract

A rapid microfluidic based capillary electrophoresis immunoassay (CEIA) was developed for on-line monitoring of glucagon secretion from pancreatic islets of Langerhans. In the device, a cell chamber containing living islets was perfused with buffers containing either high or low glucose concentration. Perfusate was continuously sampled by electroosmosis… (More)
DOI: 10.1007/s00216-012-5755-7

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@article{Shackman2012DynamicMO, title={Dynamic monitoring of glucagon secretion from living cells on a microfluidic chip.}, author={Jonathan G Shackman and Kendra R. Reid and Colleen E Dugan and Robert T. Kennedy}, journal={Analytical and bioanalytical chemistry}, year={2012}, volume={402 9}, pages={2797-803} }