Dynamic microtubule organization and mitochondrial transport are regulated by distinct Kinesin-1 pathways

Abstract

The microtubule (MT) plus-end motor kinesin heavy chain (Khc) is well known for its role in long distance cargo transport. Recent evidence showed that Khc is also required for the organization of the cellular MT network by mediating MT sliding. We found that mutations in Khc and the gene of its adaptor protein, kinesin light chain (Klc) resulted in… (More)
DOI: 10.1242/bio.015206

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