Dynamic interactions of proteins in complex networks: a more structured view.

@article{Stein2009DynamicIO,
  title={Dynamic interactions of proteins in complex networks: a more structured view.},
  author={Amelie Stein and Roland A. Pache and Pau Bernad{\'o} and Miquel Pons and Patrick Aloy},
  journal={The FEBS journal},
  year={2009},
  volume={276 19},
  pages={5390-405}
}
Virtually every process in a cell is carried out by macromolecular complexes whose actions need to be perfectly orchestrated. The synchronization and regulation of these biological functions is indeed critical and is usually carried out by complex networks of transient protein interactions. Here, we review some of the many strategies that proteins in regulatory networks use to achieve the dynamic plasticity necessary to rapidly respond to diverse cellular needs. More specifically, we present… CONTINUE READING