Dynamic interactions in malaria: host heterogeneity meets parasite polymorphism.

  title={Dynamic interactions in malaria: host heterogeneity meets parasite polymorphism.},
  author={Sunetra Gupta and Adrian V S Hill},
  journal={Proceedings. Biological sciences},
  volume={261 1362},
The spectrum of disease severity in Plasmodium falciparum malaria can be attributed to heterogeneity in parasite virulence or to heterogeneity in host factors. However, the two are not necessarily separate explanations for the same phenomena: they may actually complement each other. The conjoint effects of host and parasite heterogeneity can serve to explain certain intriguing epidemiological observations, such as, why there is a reduction in incidence of severe malaria in certain host… CONTINUE READING


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