Dynamic instability of microtubule growth

@article{Mitchison1984DynamicIO,
  title={Dynamic instability of microtubule growth},
  author={Timothy J Mitchison and Marc Kirschner},
  journal={Nature},
  year={1984},
  volume={312},
  pages={237-242}
}
We report here that microtubules in vitro coexist in growing and shrinking populations which interconvert rather infrequently. This dynamic instability is a general property of microtubules and may be fundamental in explaining cellular microtubule organization. 
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