Dynamic hyperinflation during bronchoconstriction in asthma: implications for symptom perception.

@article{Lougheed2006DynamicHD,
  title={Dynamic hyperinflation during bronchoconstriction in asthma: implications for symptom perception.},
  author={M. Diane Lougheed and Thomas Fisher and Denis E. O’Donnell},
  journal={Chest},
  year={2006},
  volume={130 4},
  pages={
          1072-81
        }
}
OBJECTIVE The objective of this study was to examine the relationship between respiratory symptom intensity and quality and dynamic lung hyperinflation (DH) during induced bronchoconstriction in asthma. PATIENTS AND METHODS Subjects with asthma (n = 116) underwent baseline spirometry and lung volume measurement followed by high-dose methacholine challenge testing (MCT) [maximum decrease in FEV(1) of 50% from baseline]. Dyspnea intensity (Borg scale) was measured after each dose of… 
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Highly Influential Citations
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Background Citations
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Methods Citations
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Results Citations
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Changes in respiratory function, notably dynamic hyperinflation, are greater in obese individuals with bronchoconstriction, which may potentially alter the perception and assessment of asthma severity in obese patients with asthma.
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